Trigger auto reply when email is clicked?

First of all, forgive me if this question has already been answered but i couldn’t find one that matches exactly what i’m trying to do (if it’s even possible)

So, i know there’s different ways to set up forms to send automatic replies, but i’m trying to skip the form completely on this one. I would like to send emails to contacts that already belong to my database (not new ones) to confirm their attendance to an event. So what i need from zapier is to figure which of the contacts clicked on the email.

My company uses Masterbase to manage their campaigns, so perhaps if i use a webhook to listen to a url on a button in the email...and then create an action that sends a reply to an inbox with the email it came from. That way i could store all the contacts that clicked in a spreadsheet or a crm. from that point i can look for duplicates and whatnot, but to know who clicked: that’s my goal.

Would this work? Is there a proper way of doing this?
All information will be greatly appreciated, thanks.